产品货号:
Z29762
中文名称:
XBP1抗体
英文名称:
Anti-XBP1 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
| 抗体名称 | Anti-XBP1 Antibody |
| 指标别名 | TREB5;X box binding protein 1;XBP 1;XBP1;XBP1s;XBP-1S;XBP1U;XBP2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC,IF,ELISA |
| 基因名称 | XBP1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Anti-XBP-1 antibody was raised against a peptide corresponding to 17 amino acids near the amino terminus of human XBP-1.The immunogen is located within amino acids 40 - 90 of XBP-1. |
| 计算分子量 | 29kDa |
| 成分 | XBP-1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | XBP-1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
| 背景资料 | X box binding protein 1 (XBP-1) is a key protein in the mammalian unfolded protein response (UPR) that protects the cell against the stress of malfolded proteins in the endoplasmic reticulum (ER).Upon sensing unfolded proteins,an ER transmembrane endonuclease and kinase termed IRE1p is activated and excises an intron from XBP-1 mRNA.The spliced XBP-1 mRNA results in a 371 amino acid protein (XBP-1s) which is then translocated to the nucleus where it binds to the regulatory elements of downstream genes.Together with other UPR transcription factors such as ATF6,XBP-1 stimulates the production of ER stress proteins including the ER resident protein chaperones glucose regulated protein (GRP) 78 and GRP94. |
| Uniprot ID | P17861 |
| 基因名全称 | X-box binding protein 1 |
| 蛋白名全称 | X-box binding protein 1 |
| 推荐稀释比 | WB:0.25~2μg/mL;IF:20μg/mL;ICC:10μg/mL;IHC:2~5μg/mL.Antibody validated:Western Blot in human samples;Immunofluorescence in human and rat samples;Immunocytochemistry in human samples;Immunohistochemistry in human,mouse,and rat samples.All other applications and species not yet tested. |
相关搜索:XBP1抗体,XBP1多抗,Anti-XBP1 Antibody
